Coenzyme Q10 (CoQ10 - Ubiquinone)

Coenzyme Q10

Coenzyme Q10
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Coenzyme Q10– ubiquinone- is a fat soluble substance similar to a vitamins. It is produced by the body and can be found in every cell. Coenzyme Q10 is found in higher amounts in certain organs, such as the heart, pancreas, kidney, and the liver (organs whose work requires a lot of energy). On the one hand, CoQ10 is not considered as vitamin (it is produced by the human body – vitamins aren’t), but there are reasons leading to its decline (like aging, smoking and certain medications intake) – so, we pay attention to CoQ10.

Coenzyme Q10 plays extremally important role in energy production process. Almost 95% of energy in the human body is produced with the participation of CoQ10. This coenzyme is important for cells growing and for the general maintenance of cells in the body. It is also an excellent antioxidant, meaning that it helps prevent oxidation damage to cells. Q10 is also beneficial for helping strengthen the heart and blood vessels in those with certain heart conditions. It may also be helpful for those with certain diseases and conditions, such as Parkinson’s Disease. Although there are claims that this nutrient may be beneficial to cancer treatment, there is not much evidence to prove this theory.

nutshell In a nutshell
nutshell Almost 95% of energy in the human body is produced with the participation of CoQ10.
nutshell Aging, smoking, and certain medications cause to decline coenzyme Q10 level.
nutshell There is not enough information to determine if there is a level of overdose for this nutrient.

Coenzyme Q10 deficiency

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Q10 deficiency It is rare for a healthy person to have a deficiency in CoQ10. Not only does the body produce this coenzyme, but it is also found in certain foods as well. However, if someone develops a CoQ10 deficiency, symptoms include fatigue, weakness, seizures, migraine headaches. Aging, smoking and certain prescription medications (like statins – cholesterol-lowering drugs) cause CoQ10 decline.

Coenzyme Q10 overdose

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Coenzyme Q10 overdose. There is not enough information to determine if there is a level of overdose for this nutrient. However, it can interfere with other medications and can cause side effects as well. Some interactions include blood thinning medications, medications to treat cancer, and medications to lower blood pressure. CoQ10 might cause nausea and vomiting, lower blood pressure, lower blood sugar, and reduce platelet counts. It may also decrease necessary oxygen to the body during intense exercise. This coenzyme should be avoided by pregnant and nursing women as safety has not been established.

Daily Recommended Intake and sources of Q10

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Daily Recommended Intake. It is rare for a healthy person to have a deficiency in CoQ10 because human body produces it enough. But in case of medication recommended amounts of Coenzyme Q10 (ubiquinone) vary depending on the condition being treated. However, these amounts range from 50 mg to 1200 mg per day in two or more doses spread out throughout the day.

The following foods have high amounts of CoQ10:
• Beef heart (100g) – 11.3 mg of CoQ10;
• Chicken heart (100g) – up to 13.0 mg of CoQ10 ;
• Pork heart (100g) – 12.8 mg of CoQ10;
• Soybean oil (100g) – up to 28.0 mg of CoQ10;
• Olive oil (100g) – up to 16.0 mg of CoQ10;
• Grapeseed oil (100g) – up to 7.3 mg of CoQ10 ;
• Sardine (100g) – up to 6.4 mg of CoQ10;
• Pork or beef liver (100g) – up to 5.4 mg of CoQ10;
• Pork or beef muscle (100g) – up to 4.5 mg of CoQ10;
• Peanuts (100g) – 2.7 mg of CoQ10.

Other important sources of CoQ10:
• Salmon;
• Tuna;
• Broccoli;
• Avocado;
• Spinach;
• Grape.

Why “Q10”?

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Why “Q10”? This coenzyme was first discovered in 1957 by researchers from University of Wisconsin–Madison Enzyme Institute and headed by Professor Fredrick L. Crane. It is also called ubiquinone. The “Q” stands for this nutrient belonging to the “Quinone” groups of chemicals while the “10” refers to the number of special units in its chemical structure.